Compare Victoza (Liraglutide) with Alternatives: What Works Best for Weight Loss and Diabetes

Compare Victoza (Liraglutide) with Alternatives: What Works Best for Weight Loss and Diabetes
Oct 29, 2025

If you’re taking Victoza (liraglutide) for type 2 diabetes or weight management, you’ve probably wondered if there’s something better. Maybe your doctor mentioned other options, or you saw ads for Ozempic or Wegovy and got curious. You’re not alone. Thousands of people on Victoza are asking the same thing: Is there a more effective, easier, or cheaper alternative?

What Victoza Actually Does

Victoza contains liraglutide, a drug that mimics a hormone your body naturally makes called GLP-1. This hormone helps your pancreas release insulin when your blood sugar rises - especially after meals. It also slows down digestion so you feel full longer. That’s why it’s used for both type 2 diabetes and, at higher doses, chronic weight management.

Most people take Victoza once a day with a pen injector. The starting dose is 0.6 mg, then it’s increased to 1.2 mg or 1.8 mg over a few weeks. It’s not a quick fix. You need to stick with it for months to see real changes in blood sugar or weight. In clinical trials, people lost about 5-8% of their body weight over a year when using Victoza alongside diet and exercise.

How Ozempic Compares to Victoza

Ozempic (semaglutide) is the most common alternative to Victoza. It’s also a GLP-1 receptor agonist, but it’s a different molecule. Semaglutide lasts longer in your body, so you only need to inject it once a week instead of every day. That’s a big deal for people who forget daily shots or find them inconvenient.

Studies show Ozempic works better than Victoza. In a head-to-head trial, people on Ozempic lost an average of 12% of their body weight over 68 weeks - compared to 6% with Victoza. Blood sugar control also improved more with Ozempic. The starting dose is 0.25 mg weekly, then it increases to 0.5 mg or 1 mg.

But here’s the catch: Ozempic isn’t officially approved for weight loss in New Zealand unless you have type 2 diabetes. If you’re using it just for weight loss, your doctor might prescribe it off-label - which can mean higher out-of-pocket costs.

Wegovy: The Weight-Loss Powerhouse

Wegovy is the same active ingredient as Ozempic - semaglutide - but it’s approved specifically for weight loss. It comes in higher doses: up to 2.4 mg weekly. This is the strongest GLP-1 medication available for obesity.

In clinical trials, people on Wegovy lost an average of 15% of their body weight over 68 weeks. Some lost over 20%. That’s more than most other weight loss drugs on the market. It’s also more effective than Victoza for weight loss - by a wide margin.

But Wegovy is expensive. In New Zealand, it’s not subsidized by PHARMAC for weight loss alone. If you don’t have type 2 diabetes, you’ll pay around $300-$400 per month out of pocket. Many people start on Victoza because it’s cheaper and then switch to Wegovy if they need stronger results.

Other GLP-1 Options: Dulaglutide and Lixisenatide

There are other GLP-1 drugs you might not have heard of, but they’re still used in New Zealand.

  • Trulicity (dulaglutide): Injected once a week. Weight loss averages 3-5%, less than Victoza. Often chosen for people who want a weekly shot but don’t need maximum weight loss.
  • Adlyxin (lixisenatide): Taken once daily, right before meals. It’s weaker for weight loss and mainly used for blood sugar control. Not commonly prescribed unless other options aren’t suitable.

Neither Trulicity nor Adlyxin are strong contenders if your main goal is weight loss. They’re more about keeping blood sugar stable without the side effects of older drugs like insulin or sulfonylureas.

Hand injecting Wegovy with glowing GLP-1 trail turning fat into healthy cells, sunlight breaking through.

Non-GLP-1 Alternatives: Metformin, SGLT2 Inhibitors, and More

You don’t have to stick with GLP-1 drugs. Other diabetes medications also help with weight loss - just not as much.

  • Metformin: The oldest, cheapest, and safest option. Most people lose 2-5% of their weight on it. It doesn’t cause low blood sugar and is often the first drug prescribed. But it doesn’t match Victoza’s weight loss results.
  • SGLT2 inhibitors (like Jardiance, Forxiga): These make your kidneys flush out sugar through urine. People lose 2-4% of their weight. They also reduce heart failure risk, which is a big plus if you have heart disease.
  • Insulin: Actually causes weight gain. If you’re on insulin and struggling to lose weight, switching to a GLP-1 drug might help.

Some doctors combine drugs - like metformin with Victoza - to get better results. That’s common practice. But combining two GLP-1 drugs (like Victoza and Ozempic) isn’t safe and isn’t done.

Side Effects: What You Might Experience

All GLP-1 drugs share similar side effects because they work the same way. The most common are nausea, vomiting, diarrhea, and constipation. These usually fade after a few weeks as your body adjusts.

More serious risks include pancreatitis, gallbladder disease, and a possible link to thyroid tumors in rats (though not proven in humans). If you have a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia, you shouldn’t take any of these drugs.

Wegovy and Ozempic tend to cause more nausea than Victoza because of the higher doses. But many people tolerate them fine once they’re on the full dose. If nausea is a problem, your doctor can slow down the dose increase.

Cost and Access in New Zealand

Cost is often the deciding factor.

  • Victoza: Subsidized by PHARMAC for type 2 diabetes. Costs about $15-$25 per prescription if you have a community services card. Not subsidized for weight loss alone.
  • Ozempic: Subsidized only if you have type 2 diabetes and meet specific criteria (like HbA1c over 7.5% despite other meds). Without subsidy, it’s $250-$350 per month.
  • Wegovy: Not subsidized at all for weight loss. Around $300-$400 per month.
  • Metformin: $5-$10 per month, fully subsidized.

If you’re paying out of pocket, Victoza is the cheapest GLP-1 option. But if you can afford it and want better results, Ozempic or Wegovy might be worth the cost.

Anthropomorphic GLP-1 drugs as characters in a floating hologram comparison, Metformin as a humble sage.

Which One Should You Choose?

There’s no single best drug. It depends on your goals, budget, and health history.

  • Best for weight loss: Wegovy (2.4 mg weekly)
  • Best balance of effectiveness and cost: Victoza (if subsidized) or Ozempic (if you have diabetes)
  • Best for simplicity: Ozempic or Trulicity (weekly shots)
  • Best for budget: Metformin
  • Best for heart protection: SGLT2 inhibitors like Forxiga

If you’re not losing enough weight on Victoza, switching to Ozempic or Wegovy is the next logical step. If cost is a barrier, talk to your doctor about starting with metformin and adding a GLP-1 later.

What Happens If You Stop?

These drugs don’t cure diabetes or obesity. They manage it. If you stop taking them, you’ll likely regain the weight you lost - often within 6 to 12 months. That’s true for Victoza, Ozempic, and Wegovy alike.

That’s why lifestyle changes matter. Even if you’re on medication, eating more protein, moving more, and getting enough sleep will help you keep the weight off. Medication makes it easier. It doesn’t replace healthy habits.

Final Thoughts

Victoza is a solid option, especially if you’re covered by PHARMAC. But if you’re not seeing the results you want - or you’re tired of daily injections - there are better choices. Ozempic and Wegovy offer stronger weight loss and fewer injections. Metformin is still the foundation for many people. And SGLT2 inhibitors bring extra heart benefits.

The key is to talk to your doctor about your goals. Are you trying to lower your HbA1c? Lose 10 kg? Reduce your risk of heart disease? Your answer will guide the choice. Don’t assume the first drug you were given is the best one for you now.

Is Victoza the same as Ozempic?

No. Victoza contains liraglutide and is taken daily. Ozempic contains semaglutide and is taken once a week. They’re both GLP-1 drugs, but semaglutide is more potent and lasts longer in the body. Ozempic generally leads to greater weight loss and better blood sugar control.

Can I switch from Victoza to Ozempic?

Yes, many people do. Your doctor will stop Victoza and start you on Ozempic at the lowest dose (0.25 mg weekly). You won’t need to overlap the two. The switch is safe and common, especially if you want better results or fewer injections.

Is Wegovy better than Victoza for weight loss?

Yes. In clinical trials, Wegovy led to 15% average weight loss over a year, compared to 6% with Victoza. Wegovy uses a higher dose of the same active ingredient as Ozempic and is specifically approved for weight loss. If your goal is maximum weight loss, Wegovy is the strongest option available.

Why is Victoza cheaper than Ozempic in New Zealand?

Victoza is subsidized by PHARMAC for type 2 diabetes, meaning the government covers most of the cost. Ozempic is only subsidized under strict conditions - usually if you’ve already tried other medications and still have high blood sugar. Without subsidy, Ozempic costs over $250 per month, while Victoza can be under $25 with a community services card.

Do GLP-1 drugs cause muscle loss?

Some weight loss from GLP-1 drugs comes from muscle, not just fat - especially if you’re not exercising or eating enough protein. To preserve muscle, aim for 1.6-2.2 grams of protein per kilogram of body weight daily and include strength training 2-3 times a week. This helps ensure most of the weight lost is fat.

Next Steps

If you’re on Victoza and not happy with your results, don’t just keep going. Schedule a chat with your doctor. Bring a list of your goals: How much weight do you want to lose? What side effects are bothering you? What are you willing to pay?

If cost is a barrier, ask about metformin or SGLT2 inhibitors first. They’re cheaper and still effective. If you’re ready to upgrade, ask about Ozempic or Wegovy. Many people find the weekly injection easier than daily ones - and the results are worth it.

Medication is a tool. It doesn’t replace diet, movement, or sleep - but it can make those things work better. The right drug for you is the one that fits your life, your budget, and your goals.

Miranda Rathbone

Miranda Rathbone

I am a pharmaceutical specialist working in regulatory affairs and clinical research. I regularly write about medication and health trends, aiming to make complex information understandable and actionable. My passion lies in exploring advances in drug development and their real-world impact. I enjoy contributing to online health journals and scientific magazines.

9 Comments

  • Alex Hundert
    Alex Hundert
    October 30, 2025 AT 23:32

    I switched from Victoza to Ozempic last year and honestly? Life changed. Daily shots were a nightmare-I’d forget, or be at work and panic because I didn’t have my pen. Once a week? I set a calendar alert and that’s it. Lost 14% of my body weight without even trying that hard. The nausea hit hard at first, but after 3 weeks, it vanished. Worth every penny.

    Also, if you’re on a budget, ask your doc about metformin first. It’s not sexy, but it’s the backbone of this whole thing. I stayed on it alongside Ozempic and it helped with the brain fog.

    Don’t let cost scare you off. Talk to your pharmacist about patient assistance programs. They exist.

  • Emily Kidd
    Emily Kidd
    November 1, 2025 AT 11:47

    ok so i just started victoza and honestly the nausea is making me want to cry. i thought it was gonna be like ‘oh cool i’ll lose weight’ but nope, now i feel like i’m gonna barf every time i eat. anyone else? and like, how long does this last? i dont wanna quit but i also dont wanna live like this.

    ps: i miss pizza so bad.

  • Justin Cheah
    Justin Cheah
    November 2, 2025 AT 10:47

    Let me tell you what they don’t want you to know. GLP-1 drugs are not medicine-they’re a corporate scam designed to keep you dependent while Big Pharma jacks up prices. Ozempic? Wegovy? Same molecule. Same factory. Same Chinese supply chain. The only difference is the label and the price tag. PHARMAC’s ‘subsidy rules’? A smokescreen. They’re rationing access because they know if everyone got the best drug, the system would collapse. They want you stuck on Victoza because it’s cheaper to produce and easier to control.

    And don’t get me started on metformin. It’s been around since the 1950s. Why? Because it’s a cheap, old, unpatentable drug. The real breakthrough isn’t semaglutide-it’s the fact that we’re being sold a new version of the same old lie. You think you’re getting health? You’re getting a subscription. The weight comes off. The weight goes back on. And you’re still paying $400 a month for the privilege. Wake up.

    Also, muscle loss? That’s not a side effect-that’s a feature. They want you weak. Weak people don’t question the system.

    And yes, I’ve read the rat studies. And no, I don’t trust the FDA. Or PHARMAC. Or your doctor. They’re all in the machine.

  • caiden gilbert
    caiden gilbert
    November 4, 2025 AT 04:43

    Victoza felt like carrying a tiny, angry wasp in my pancreas for a year. Then I switched to Ozempic. The wasp? It went on vacation. Weekly shots? I forget I’m even on meds half the time. Lost 18 lbs in 3 months without changing my diet much. Honestly? It’s not magic-it’s just… less exhausting. The nausea was real for the first two weeks, but I treated it like a bad hangover and kept going. Now I’m at my lowest weight since college.

    And yeah, Wegovy sounds like the superhero version, but if you’re not broke, why not start with Ozempic? It’s like getting a Tesla when you’ve been driving a Prius. You don’t need the Model S to feel the difference.

    Also, protein. Eat more of it. I started snacking on hard-boiled eggs and jerky. Muscle didn’t vanish. Just the flab.

  • phenter mine
    phenter mine
    November 5, 2025 AT 04:57

    i just wanna say i been on victoza for 8 months and lost 11kg and i feel amazing!! the only thing is i keep misspelling things now like i think my brain is rewired?? but my sugar is so much better and i dont crave sweets anymore. my doc said to keep going and if i wanna upgrade later then ozempic is the move. also i started walking 30 mins a day and it made a huge diff. thanks for this post!!

  • Aditya Singh
    Aditya Singh
    November 6, 2025 AT 12:02

    Let’s be clear: GLP-1 agonists are pharmacokinetic tools with a narrow therapeutic index in the context of metabolic syndrome management. The pharmacodynamic profile of liraglutide exhibits a half-life of approximately 13 hours, whereas semaglutide demonstrates a terminal half-life exceeding 160 hours due to albumin binding and FcRn-mediated recycling. The clinical efficacy differential between Victoza and Ozempic is statistically significant (p < 0.001) in head-to-head trials, but the effect size is confounded by baseline BMI, insulin resistance, and dietary adherence. Furthermore, the PHARMAC subsidy model reflects a cost-utility analysis predicated on QALY thresholds that systematically disadvantage non-diabetic obesity patients. You’re not being denied access-you’re being triaged by actuarial logic. If you’re not diabetic, you’re a non-priority patient. Welcome to neoliberal healthcare.

    And yes, muscle loss is real. The catabolic effect of GLP-1s is mediated through suppression of ghrelin and downregulation of mTORC1 signaling. You need leucine thresholds >2.5g per meal to mitigate proteolysis. Otherwise, you’re just losing lean mass and looking like a deflated balloon. Eat more eggs. Lift weights. Or accept your fate as a metabolic statistic.

  • Katherine Reinarz
    Katherine Reinarz
    November 7, 2025 AT 20:41

    OMG I JUST FOUND OUT MY BOSS IS ON WEGOVY AND SHE LOST 40 POUNDS IN 6 MONTHS AND NOW SHE WEARS A SIZE 4 AND I’M STILL IN SIZE 14 AND I FEEL LIKE A FAILURE AND SHE JUST LAUGHED AND SAID ‘OH I JUST TAKE IT’ AND I WANT TO CRY AND ALSO I THINK SHE’S HIDING IT FROM HER HUSBAND BECAUSE HE THINKS SHE’S ‘JUST EATING LESS’ BUT I KNOW THE TRUTH AND I NEED TO KNOW IF I CAN GET IT WITHOUT A PRESCRIPTION BECAUSE I CAN’T AFFORD IT AND I’M SO JEALOUS AND ALSO DID YOU KNOW THEY PUT LITHIUM IN THE INJECTORS TO MAKE YOU CALM??? I READ IT ON A FORUM AND NOW I’M SCARED TO TAKE ANYTHING I DON’T KNOW WHAT TO DO ANYONE PLEASE HELP ME I’M SO ANXIOUS ABOUT THIS I CAN’T SLEEP

  • John Kane
    John Kane
    November 9, 2025 AT 10:12

    Hey everyone, I just want to say-this thread is actually really helpful. I’ve been on Victoza for a year, and I was starting to feel like I was stuck. But reading your stories? It made me realize I’m not alone. I’ve been hesitant to bring up switching meds because I didn’t want to seem ungrateful for what I have. But if Ozempic gives me back my energy and my confidence, why wouldn’t I ask?

    And to the person worried about nausea? I was terrified too. My doc had me start at 0.25 mg and I waited six weeks before bumping up. Took the edge off. Also, ginger tea. Seriously. It’s weird, but it helped. And protein snacks between meals? Game changer.

    Don’t feel bad if you’re on metformin. It’s not glamorous, but it’s saved millions of lives. And if you’re on Wegovy? You’re not a drug addict-you’re someone who’s fighting for their health. That’s brave.

    And to the guy who thinks it’s all a conspiracy? I get it. The system’s broken. But don’t let that stop you from trying to make your own life better. One injection, one meal, one walk at a time.

    You’ve got this.

  • Callum Breden
    Callum Breden
    November 11, 2025 AT 08:45

    The clinical data presented here is fundamentally misleading. The weight loss metrics cited are derived from trials with stringent inclusion criteria: patients with BMI >30, no prior bariatric surgery, and strict dietary supervision. Real-world adherence is approximately 40% at 12 months, rendering the 15% weight loss figure statistically irrelevant to the general population. Furthermore, the cost-benefit analysis is grossly distorted by the omission of long-term cardiovascular outcomes. No GLP-1 agonist has demonstrated mortality reduction in non-diabetic populations. The elevation in heart rate observed with semaglutide remains unaddressed. And the suggestion that switching from Victoza to Ozempic is ‘safe and common’ is a dangerous oversimplification. Dose titration protocols are not interchangeable. Improper transition can precipitate severe gastrointestinal dysmotility and pancreatitis. This post reads like a pharmaceutical marketing brochure disguised as medical advice. The author is either dangerously naive or complicit.

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